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Molecular Mechanisms of Apoptosis Induction and Its Regulation by Fatty Acids in Pancreatic β-Cells

Pancreatic β-cell failure and death contribute significantly to the pathogenesis of type 2 diabetes. One of the main factors responsible for β-cell dysfunction and subsequent cell death is chronic exposure to increased concentrations of FAs (fatty acids). The effect of FAs seems to depend particular...

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Detalles Bibliográficos
Autores principales: Šrámek, Jan, Němcová-Fürstová, Vlasta, Kovář, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074590/
https://www.ncbi.nlm.nih.gov/pubmed/33924206
http://dx.doi.org/10.3390/ijms22084285