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Coronavirus helicases: attractive and unique targets of antiviral drug-development and therapeutic patents

Introduction: Coronaviruses encode a helicase that is essential for viral replication and represents an excellent antiviral target. However, only a few coronavirus helicase inhibitors have been patented. These patents include drug-like compound SSYA10-001, aryl diketo acids (ADK), and dihydroxychrom...

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Detalles Bibliográficos
Autores principales: Spratt, Austin N., Gallazzi, Fabio, Quinn, Thomas P., Lorson, Christian L., Sönnerborg, Anders, Singh, Kamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074651/
https://www.ncbi.nlm.nih.gov/pubmed/33593200
http://dx.doi.org/10.1080/13543776.2021.1884224