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Transcryptomic Analysis of Human Brain-Microvascular Endothelial Response to -Pericytes: Cell Orientation Defines Barrier Function

Pericytes facilitate blood–brain barrier (BBB) integrity; however, the mechanisms involved remain unclear. Hence, using co-cultures of human cerebral microvascular endothelial cells (ECs) and vascular pericytes (PCs) in different spatial arrangements, as well as PC conditioned media, we investigated...

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Detalles Bibliográficos
Autores principales: Kurmann, Lisa, Okoniewski, Michal, Ogunshola, Omolara O., Leeners, Brigitte, Imthurn, Bruno, Dubey, Raghvendra K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074760/
https://www.ncbi.nlm.nih.gov/pubmed/33924251
http://dx.doi.org/10.3390/cells10040963