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Highly efficient multiplex genetic engineering of porcine primary fetal fibroblasts
BACKGROUND: Genetically engineered porcine donors are a potential solution for the shortage of human organs for transplantation. Incompatibilities between humans and porcine donors are largely due to carbohydrate xenoantigens on the surface of porcine cells, provoking an immune response which leads...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074785/ https://www.ncbi.nlm.nih.gov/pubmed/33937740 http://dx.doi.org/10.1016/j.sopen.2020.11.003 |