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Highly efficient multiplex genetic engineering of porcine primary fetal fibroblasts

BACKGROUND: Genetically engineered porcine donors are a potential solution for the shortage of human organs for transplantation. Incompatibilities between humans and porcine donors are largely due to carbohydrate xenoantigens on the surface of porcine cells, provoking an immune response which leads...

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Detalles Bibliográficos
Autores principales:	Klapholz, Benjamin, Levy, Heather, Kumbha, Ramesh, Hosny, Nora, D'Angelo, Michael E., Hering, Bernhard J., Burlak, Christopher
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074785/ https://www.ncbi.nlm.nih.gov/pubmed/33937740 http://dx.doi.org/10.1016/j.sopen.2020.11.003

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