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Decreased Treg Cell and TCR Expansion Are Involved in Long-Lasting Graves’ Disease

Graves’ disease (GD) is a T cell-mediated organ-specific autoimmune disorder. GD patients who have taken anti-thyroid drugs (ATDs) for more than 5 years with positive anti-thyroid stimulating hormone receptor autoantibodies value were defined as persistent GD (pGD). To develop novel immunotherapies...

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Detalles Bibliográficos
Autores principales: Chen, Ziyi, Liu, Yufeng, Hu, Shiqian, Zhang, Meng, Shi, Bingyin, Wang, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074859/
https://www.ncbi.nlm.nih.gov/pubmed/33912135
http://dx.doi.org/10.3389/fendo.2021.632492