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Effect of spin labelling on the aggregation kinetics of yeast prion protein Ure2

Amyloid formation is involved in a wide range of neurodegenerative diseases including Alzheimer's and prion diseases. Structural understanding of the amyloid is critical to delineate the mechanism of aggregation and its pathological spreading. Site-directed spin labelling has emerged as a power...

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Detalles Bibliográficos
Autores principales: Liu, Emilie N., Park, Giovanna, Nohara, Junsuke, Guo, Zhefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8074925/
https://www.ncbi.nlm.nih.gov/pubmed/33959337
http://dx.doi.org/10.1098/rsos.201747