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Understanding interactions between risk factors, and assessing the utility of the additive and multiplicative models through simulations

Understanding the genetic background of complex diseases requires the expansion of studies beyond univariate associations. Therefore, it is important to use interaction assessments of risk factors in order to discover whether, and how genetic risk variants act together on disease development. The pr...

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Detalles Bibliográficos
Autores principales: Diaz-Gallo, Lina-Marcela, Brynedal, Boel, Westerlind, Helga, Sandberg, Rickard, Ramsköld, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075235/
https://www.ncbi.nlm.nih.gov/pubmed/33901204
http://dx.doi.org/10.1371/journal.pone.0250282