Cargando…
Understanding interactions between risk factors, and assessing the utility of the additive and multiplicative models through simulations
Understanding the genetic background of complex diseases requires the expansion of studies beyond univariate associations. Therefore, it is important to use interaction assessments of risk factors in order to discover whether, and how genetic risk variants act together on disease development. The pr...
Autores principales: | Diaz-Gallo, Lina-Marcela, Brynedal, Boel, Westerlind, Helga, Sandberg, Rickard, Ramsköld, Daniel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075235/ https://www.ncbi.nlm.nih.gov/pubmed/33901204 http://dx.doi.org/10.1371/journal.pone.0250282 |
Ejemplares similares
-
Systematic approach demonstrates enrichment of multiple interactions between non-HLA risk variants and HLA-DRB1 risk alleles in rheumatoid arthritis
por: Diaz-Gallo, Lina-Marcela, et al.
Publicado: (2018) -
Importance of Human Leukocyte Antigen (HLA) Class I and II Alleles on the Risk of Multiple Sclerosis
por: Link, Jenny, et al.
Publicado: (2012) -
Efficient and Comprehensive Representation of Uniqueness for Next-Generation Sequencing by Minimum Unique Length Analyses
por: Storvall, Helena, et al.
Publicado: (2013) -
An Abundance of Ubiquitously Expressed Genes Revealed by Tissue Transcriptome Sequence Data
por: Ramsköld, Daniel, et al.
Publicado: (2009) -
Genome-wide mapping of promoter-anchored interactions with close to single-enhancer resolution
por: Sahlén, Pelin, et al.
Publicado: (2015)