Transport of Alzheimer’s associated amyloid-β catalyzed by P-glycoprotein

P-glycoprotein (P-gp) is a critical membrane transporter in the blood brain barrier (BBB) and is implicated in Alzheimer’s disease (AD). However, previous studies on the ability of P-gp to directly transport the Alzheimer’s associated amyloid-β (Aβ) protein have produced contradictory results. Here...

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Detalles Bibliográficos
Autores principales: McCormick, James W., Ammerman, Lauren, Chen, Gang, Vogel, Pia D., Wise, John G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075256/
https://www.ncbi.nlm.nih.gov/pubmed/33901197
http://dx.doi.org/10.1371/journal.pone.0250371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075256/
https://www.ncbi.nlm.nih.gov/pubmed/33901197
http://dx.doi.org/10.1371/journal.pone.0250371

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