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Long Noncoding RNA SNHG1 Knockdown Ameliorates Apoptosis, Oxidative Stress and Inflammation in Models of Parkinson’s Disease by Inhibiting the miR-125b-5p/MAPK1 Axis

BACKGROUND: Parkinson’s disease (PD) is a prevalent neurodegenerative disease. Long noncoding RNA small molecule RNA host gene 1 (SNHG1) has been reported to play critical roles in Parkinson’s disease (PD) progression. The study aimed to further elucidate the mechanism of SNHG1 in PD pathogenesis. M...

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Detalles Bibliográficos
Autores principales: Xiao, Xiao, Tan, Zhiwen, Jia, Min, Zhou, Xiaoli, Wu, Kemei, Ding, Yanbing, Li, Wenjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075359/
https://www.ncbi.nlm.nih.gov/pubmed/33911864
http://dx.doi.org/10.2147/NDT.S286778