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COP9 Signalosome Subunit 3 Restricts Neuroinflammatory Responses During Cerebral Ischemia/Reperfusion Injury Through Stabilizing Suppressor of Cytokine Signaling 3 Protein

BACKGROUND: The suppressor of cytokine signaling 3 (SOCS3) is a specific negative regulator of signal transducer and activator of transcription 3 (STAT3) signaling, which is predominantly activated to induce neuroinflammatory response in microglia and functions essential roles during cerebral ischem...

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Detalles Bibliográficos
Autores principales: Liang, En, Li, Xiaojun, Fu, Wenjun, Zhao, Changtong, Yang, Baoying, Yang, Zhonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075360/
https://www.ncbi.nlm.nih.gov/pubmed/33911869
http://dx.doi.org/10.2147/NDT.S298966