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Sexual Dimorphism in the 3xTg-AD Mouse Model and Its Impact on Pre-Clinical Research

Female sex is a leading risk factor for developing Alzheimer’s disease (AD). Sexual dimorphism in AD is gaining attention as clinical data show that women are not only more likely to develop AD but also to experience worse pathology and faster cognitive decline. Pre-clinical AD research in animal mo...

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Detalles Bibliográficos
Autores principales: Dennison, Jessica L., Ricciardi, Natalie R., Lohse, Ines, Volmar, Claude-Henry, Wahlestedt, Claes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075398/
https://www.ncbi.nlm.nih.gov/pubmed/33459720
http://dx.doi.org/10.3233/JAD-201014