Defects in translation-dependent quality control pathways lead to convergent molecular and neurodevelopmental pathology

Translation-dependent quality control pathways such as no-go decay (NGD), non-stop decay (NSD), and nonsense-mediated decay (NMD) govern protein synthesis and proteostasis by resolving non-translating ribosomes and preventing the production of potentially toxic peptides derived from faulty and aberr...

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Detalles Bibliográficos
Autores principales: Terrey, Markus, Adamson, Scott I, Chuang, Jeffrey H, Ackerman, Susan L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075583/
https://www.ncbi.nlm.nih.gov/pubmed/33899734
http://dx.doi.org/10.7554/eLife.66904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075583/
https://www.ncbi.nlm.nih.gov/pubmed/33899734
http://dx.doi.org/10.7554/eLife.66904

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