Pharmacokinetics of 10-Hydroxy Mesaconitine in Rat Plasma by Ultra-Performance Liquid Chromatography-Tandem Quadrupole Mass Spectrometry

Mesaconitine is the predominant active ingredient in Aconitum carmichaelii Debx. The compound 10-hydroxy mesaconitine is one known metabolite of mesaconitine and is toxic. In order to better understand its pharmacokinetics, UPLC-MS/MS was used in this paper to measure the concentration of 10-hydroxy...

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Detalles Bibliográficos
Autores principales: Yang, Jinzhao, Zeng, Guowu, Ma, Jianshe, Wang, Xianqin, Zhou, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075697/
https://www.ncbi.nlm.nih.gov/pubmed/33959404
http://dx.doi.org/10.1155/2021/6640184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075697/
https://www.ncbi.nlm.nih.gov/pubmed/33959404
http://dx.doi.org/10.1155/2021/6640184

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