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Inhibition of UCHL1 by LDN-57444 attenuates Ang II–Induced atrial fibrillation in mice
Atrial fibrillation (AF) is the most common human arrhythmia in clinical practice and may be promoted by atrial inflammation and fibrosis. Ubiquitination is an important posttranslational modification process that is reversed by deubiquitinating enzymes (DUBs). DUBs play critical roles in modulating...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075865/ https://www.ncbi.nlm.nih.gov/pubmed/31700166 http://dx.doi.org/10.1038/s41440-019-0354-z |