Identification of a novel EphB4 phosphodegron regulated by the autocrine IGFII/IR(A) axis in malignant mesothelioma

Malignant mesothelioma is a deadly disease with limited therapeutic options. EphB4 is an oncogenic tyrosine kinase receptor expressed in malignant mesothelioma as well as in a variety of cancers. It is involved in tumor microenvironment mediating angiogenesis and invasive cellular effects via both E...

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Detalles Bibliográficos
Autores principales: Scalia, Pierluigi, Pandini, Giuseppe, Carnevale, Vincenzo, Giordano, Antonio, Williams, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075896/
https://www.ncbi.nlm.nih.gov/pubmed/31270394
http://dx.doi.org/10.1038/s41388-019-0854-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075896/
https://www.ncbi.nlm.nih.gov/pubmed/31270394
http://dx.doi.org/10.1038/s41388-019-0854-y

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