Intestinal CD8(+) T cell responses are abundantly induced early in human development but show impaired cytotoxic effector capacities

Gastrointestinal viral infections are a major global cause of disease and mortality in infants. Cytotoxic CD8(+) T cells are critical to achieve viral control. However, studies investigating the development of CD8(+) T cell immunity in human tissues early in life are lacking. Here, we investigated t...

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Detalles Bibliográficos
Autores principales: Schreurs, R. R. C. E., Sagebiel, A. F., Steinert, F. L., Highton, A. J., Klarenbeek, P. L., Drewniak, A., Bakx, R., The, S. M. L., Ribeiro, C. M. S., Perez, D., Reinshagen, K., Geijtenbeek, T. B. H., van Goudoever, J. B., Bunders, M. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075922/
https://www.ncbi.nlm.nih.gov/pubmed/33772147
http://dx.doi.org/10.1038/s41385-021-00382-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075922/
https://www.ncbi.nlm.nih.gov/pubmed/33772147
http://dx.doi.org/10.1038/s41385-021-00382-x

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