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The Indian cobra reference genome and transcriptome enables comprehensive identification of venom toxins

Snakebite envenoming is a serious and neglected tropical disease that kills ~100,000 people annually. High-quality, genome-enabled comprehensive characterization of toxin genes will facilitate development of effective humanized recombinant antivenom. We report a de novo near-chromosomal genome assem...

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Detalles Bibliográficos
Autores principales: Suryamohan, Kushal, Krishnankutty, Sajesh P., Guillory, Joseph, Jevit, Matthew, Schröder, Markus S., Wu, Meng, Kuriakose, Boney, Mathew, Oommen K., Perumal, Rajadurai C., Koludarov, Ivan, Goldstein, Leonard D., Senger, Kate, Dixon, Mandumpala Davis, Velayutham, Dinesh, Vargas, Derek, Chaudhuri, Subhra, Muraleedharan, Megha, Goel, Ridhi, Chen, Ying-Jiun J., Ratan, Aakrosh, Liu, Peter, Faherty, Brendan, de la Rosa, Guillermo, Shibata, Hiroki, Baca, Miriam, Sagolla, Meredith, Ziai, James, Wright, Gus A., Vucic, Domagoj, Mohan, Sangeetha, Antony, Aju, Stinson, Jeremy, Kirkpatrick, Donald S., Hannoush, Rami N., Durinck, Steffen, Modrusan, Zora, Stawiski, Eric W., Wiley, Kristen, Raudsepp, Terje, Kini, R. Manjunatha, Zachariah, Arun, Seshagiri, Somasekar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075977/
https://www.ncbi.nlm.nih.gov/pubmed/31907489
http://dx.doi.org/10.1038/s41588-019-0559-8