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Metabolic activation and colitis pathogenesis is prevented by lymphotoxin β receptor expression in neutrophils

Inflammatory bowel disease is characterized by an exacerbated intestinal immune response, but the critical mechanisms regulating immune activation remain incompletely understood. We previously reported that the TNF-superfamily molecule TNFSF14 (LIGHT) is required for preventing severe disease in mou...

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Detalles Bibliográficos
Autores principales: Riffelmacher, Thomas, Giles, Daniel A., Zahner, Sonja, Dicker, Martina, Andreyev, Alexander Y., McArdle, Sara, Perez-Jeldres, Tamara, van der Gracht, Esmé, Murray, Mallory Paynich, Hartmann, Nadine, Tumanov, Alexei V., Kronenberg, Mitchell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075978/
https://www.ncbi.nlm.nih.gov/pubmed/33568785
http://dx.doi.org/10.1038/s41385-021-00378-7