Cargando…
Metabolic activation and colitis pathogenesis is prevented by lymphotoxin β receptor expression in neutrophils
Inflammatory bowel disease is characterized by an exacerbated intestinal immune response, but the critical mechanisms regulating immune activation remain incompletely understood. We previously reported that the TNF-superfamily molecule TNFSF14 (LIGHT) is required for preventing severe disease in mou...
Autores principales: | Riffelmacher, Thomas, Giles, Daniel A., Zahner, Sonja, Dicker, Martina, Andreyev, Alexander Y., McArdle, Sara, Perez-Jeldres, Tamara, van der Gracht, Esmé, Murray, Mallory Paynich, Hartmann, Nadine, Tumanov, Alexei V., Kronenberg, Mitchell |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075978/ https://www.ncbi.nlm.nih.gov/pubmed/33568785 http://dx.doi.org/10.1038/s41385-021-00378-7 |
Ejemplares similares
-
The Tumor Necrosis Factor Superfamily Members TNFSF14 (LIGHT), Lymphotoxin β and Lymphotoxin β Receptor Interact to Regulate Intestinal Inflammation
por: Giles, Daniel A., et al.
Publicado: (2018) -
When Insult Is Added to Injury: Cross Talk between ILCs and Intestinal Epithelium in IBD
por: van der Gracht, Esmé, et al.
Publicado: (2016) -
CD4(+)-mediated colitis in mice is independent of the GPR183 and GPR18 pathways
por: Dicker, Martina, et al.
Publicado: (2022) -
Divergent metabolic programmes control two populations of MAIT cells that protect the lung
por: Riffelmacher, Thomas, et al.
Publicado: (2023) -
Lymphotoxin β Receptor Controls T Cell Progenitor Entry to the Thymus
por: Lucas, Beth, et al.
Publicado: (2016)