Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma

TYK2 is a member of the JAK family of tyrosine kinases that is involved in chromosomal translocation-induced fusion proteins found in anaplastic large cell lymphomas (ALCL) that lack rearrangements activating the anaplastic lymphoma kinase (ALK). Here we demonstrate that TYK2 is highly expressed in...

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Detalles Bibliográficos
Autores principales: Prutsch, Nicole, Gurnhofer, Elisabeth, Suske, Tobias, Liang, Huan Chang, Schlederer, Michaela, Roos, Simone, Wu, Lawren C., Simonitsch-Klupp, Ingrid, Alvarez-Hernandez, Andrea, Kornauth, Christoph, Leone, Dario A., Svinka, Jasmin, Eferl, Robert, Limberger, Tanja, Aufinger, Astrid, Shirsath, Nitesh, Wolf, Peter, Hielscher, Thomas, Sternberg, Christina, Aberger, Fritz, Schmoellerl, Johannes, Stoiber, Dagmar, Strobl, Birgit, Jäger, Ulrich, Staber, Philipp B., Grebien, Florian, Moriggl, Richard, Müller, Mathias, Inghirami, Giorgio G., Sanda, Takaomi, Look, A. Thomas, Turner, Suzanne D., Kenner, Lukas, Merkel, Olaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076043/
https://www.ncbi.nlm.nih.gov/pubmed/30131584
http://dx.doi.org/10.1038/s41375-018-0239-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076043/
https://www.ncbi.nlm.nih.gov/pubmed/30131584
http://dx.doi.org/10.1038/s41375-018-0239-1

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