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PHD Finger Protein 19 Promotes Cardiac Hypertrophy via Epigenetically Regulating SIRT2

Epigenetic regulations essentially participate in the development of cardiomyocyte hypertrophy. PHD finger protein 19 (PHF19) is a polycomb protein that controls H3K36me3 and H3K27me3. However, the roles of PHF19 in cardiac hypertrophy remain unknown. Here in this work, we observed that PHF19 promot...

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Detalles Bibliográficos
Autores principales: Gu, Wei, Cheng, Yutong, Wang, Su, Sun, Tao, Li, Zhizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076129/
https://www.ncbi.nlm.nih.gov/pubmed/33611744
http://dx.doi.org/10.1007/s12012-021-09639-0