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Prostaglandin F2α agonists induced enhancement in collagen1 expression is involved in the pathogenesis of the deepening of upper eyelid sulcus

Previous our study reported that three-dimension (3D) cultures of human orbital fibroblasts (HOFs) replicated the etiology of deepening of the upper eyelid sulcus (DUES) caused by prostaglandin F2α analogues (PGF2α-ags). To examine this further, the effects of PGF2α-ags on HOFs were characterized by...

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Detalles Bibliográficos
Autores principales: Itoh, Kaku, Ida, Yosuke, Ohguro, Hiroshi, Hikage, Fumihito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076191/
https://www.ncbi.nlm.nih.gov/pubmed/33903711
http://dx.doi.org/10.1038/s41598-021-88562-4