Estimation of the timing of BAP1 mutation in uveal melanoma progression

Uveal melanoma is the most common primary intraocular malignancy. A vast majority of metastasizing tumors have mutations in the BAP1 gene. Here, we investigate the spatiotemporal timing of these mutations. The size of 177 uveal melanomas and 8.3 million individual tumor cells was measured. BAP1 sequ...

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Detalles Bibliográficos
Autores principales: Uner, Ogul E., See, Thonnie Rose O., Szalai, Eszter, Grossniklaus, Hans E., Stålhammar, Gustav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076235/
https://www.ncbi.nlm.nih.gov/pubmed/33903674
http://dx.doi.org/10.1038/s41598-021-88390-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076235/
https://www.ncbi.nlm.nih.gov/pubmed/33903674
http://dx.doi.org/10.1038/s41598-021-88390-6

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