Quantitative imaging of membrane contact sites for sterol transfer between endo-lysosomes and mitochondria in living cells

Mitochondria receive cholesterol from late endosomes and lysosomes (LE/LYSs) or from the plasma membrane for production of oxysterols and steroid hormones. This process depends on the endo-lysosomal sterol transfer protein Niemann Pick C2 (NPC2). Using the intrinsically fluorescent cholesterol analo...

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Detalles Bibliográficos
Autores principales: Juhl, Alice Dupont, Heegaard, Christian W., Werner, Stephan, Schneider, Gerd, Krishnan, Kathiresan, Covey, Douglas F., Wüstner, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076251/
https://www.ncbi.nlm.nih.gov/pubmed/33903617
http://dx.doi.org/10.1038/s41598-021-87876-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076251/
https://www.ncbi.nlm.nih.gov/pubmed/33903617
http://dx.doi.org/10.1038/s41598-021-87876-7

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