Bioinformatics methods for identification of amyloidogenic peptides show robustness to misannotated training data

Several disorders are related to amyloid aggregation of proteins, for example Alzheimer’s or Parkinson’s diseases. Amyloid proteins form fibrils of aggregated beta structures. This is preceded by formation of oligomers—the most cytotoxic species. Determining amyloidogenicity is tedious and costly. T...

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Detalles Bibliográficos
Autores principales: Szulc, Natalia, Burdukiewicz, Michał, Gąsior-Głogowska, Marlena, Wojciechowski, Jakub W., Chilimoniuk, Jarosław, Mackiewicz, Paweł, Šneideris, Tomas, Smirnovas, Vytautas, Kotulska, Malgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076271/
https://www.ncbi.nlm.nih.gov/pubmed/33903613
http://dx.doi.org/10.1038/s41598-021-86530-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076271/
https://www.ncbi.nlm.nih.gov/pubmed/33903613
http://dx.doi.org/10.1038/s41598-021-86530-6

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