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Transitions in oral and gut microbiome of HPV+ oropharyngeal squamous cell carcinoma following definitive chemoradiotherapy (ROMA LA-OPSCC study)

BACKGROUND: Oral and gut microbiomes have emerged as potential biomarkers in cancer. We characterised the oral and gut microbiomes in a prospective observational cohort of HPV+ oropharyngeal squamous cell carcinoma (OPSCC) patients and evaluated the impact of chemoradiotherapy (CRT). METHODS: Saliva...

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Detalles Bibliográficos
Autores principales: Oliva, Marc, Schneeberger, Pierre H. H., Rey, Victor, Cho, Matthew, Taylor, Rachel, Hansen, Aaron R., Taylor, Kirsty, Hosni, Ali, Bayley, Andrew, Hope, Andrew J., Bratman, Scott V., Ringash, Jolie, Singh, Simron, Weinreb, Ilan, Perez-Ordoñez, Bayardo, Chepeha, Douglas, Waldron, John, Xu, Wei, Guttman, David, Siu, Lillian L., Coburn, Bryan, Spreafico, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076306/
https://www.ncbi.nlm.nih.gov/pubmed/33750907
http://dx.doi.org/10.1038/s41416-020-01253-1