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Use of omeprazole, the proton pump inhibitor, as a potential therapy for the capecitabine-induced hand-foot syndrome

Hand-foot syndrome (HFS), also known as palmar-plantar erythrodysesthesia (PPE), is a major side effect of capecitabine. Although the pathogenesis of HFS remains unknown, some studies suggested a potential involvement of inflammation in its pathogenesis. Proton pump inhibitors (PPIs) have been repor...

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Detalles Bibliográficos
Autores principales: Hiromoto, Shiori, Kawashiri, Takehiro, Yamanaka, Natsumi, Kobayashi, Daisuke, Mine, Keisuke, Inoue, Mizuki, Uchida, Mayako, Shimazoe, Takao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076322/
https://www.ncbi.nlm.nih.gov/pubmed/33903667
http://dx.doi.org/10.1038/s41598-021-88460-9