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T Cell-Mediated Immune Responses to AAV and AAV Vectors
Adeno-associated virus (AAV)-mediated gene transfer has benefited patients with inherited diseases, such as hemophilia B, by achieving long-term expression of the therapeutic transgene. Nevertheless, challenges remain due to rejection of AAV-transduced cells, which in some, but not all, patients can...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076552/ https://www.ncbi.nlm.nih.gov/pubmed/33927727 http://dx.doi.org/10.3389/fimmu.2021.666666 |