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Characteristics of Cohesin Mutation in Acute Myeloid Leukemia and Its Clinical Significance
The occurrence of gene mutation is a major contributor to the initiation and propagation of acute myeloid leukemia (AML). Accumulating evidence suggests that genes encoding cohesin subunits have a high prevalence of mutations in AML, especially in the t(8;21) subtype. Therefore, it is important to u...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076553/ https://www.ncbi.nlm.nih.gov/pubmed/33928020 http://dx.doi.org/10.3389/fonc.2021.579881 |