Characteristics of Cohesin Mutation in Acute Myeloid Leukemia and Its Clinical Significance

The occurrence of gene mutation is a major contributor to the initiation and propagation of acute myeloid leukemia (AML). Accumulating evidence suggests that genes encoding cohesin subunits have a high prevalence of mutations in AML, especially in the t(8;21) subtype. Therefore, it is important to u...

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Detalles Bibliográficos
Autores principales: Han, Caixia, Gao, Xuefeng, Li, Yonghui, Zhang, Juan, Yang, Erna, Zhang, Li, Yu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076553/
https://www.ncbi.nlm.nih.gov/pubmed/33928020
http://dx.doi.org/10.3389/fonc.2021.579881

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