Impaired ATG16L-Dependent Autophagy Promotes Renal Interstitial Fibrosis in Chronic Renal Graft Dysfunction Through Inducing EndMT by NF-κB Signal Pathway

Chronic renal graft dysfunction (CAD) is caused by multiple factors, including glomerular sclerosis, inflammation, interstitial fibrosis and tubular atrophy (IF/TA). However, the most prominent elements of CAD are IF/TA. Our studies have confirmed that endothelial-mesenchymal transition (EndMT) is a...

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Detalles Bibliográficos
Autores principales: Gui, Zeping, Suo, Chuanjian, Wang, Zijie, Zheng, Ming, Fei, Shuang, Chen, Hao, Sun, Li, Han, Zhijian, Tao, Jun, Ju, Xiaobin, Yang, Haiwei, Gu, Min, Tan, Ruoyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076642/
https://www.ncbi.nlm.nih.gov/pubmed/33927720
http://dx.doi.org/10.3389/fimmu.2021.650424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076642/
https://www.ncbi.nlm.nih.gov/pubmed/33927720
http://dx.doi.org/10.3389/fimmu.2021.650424

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