BMI1 Drives Steroidogenesis Through Epigenetically Repressing the p38 MAPK Pathway

Testosterone biosynthesis progressively decreases in aging males primarily as a result of functional changes to Leydig cells. Despite this, the mechanisms underlying steroidogenesis remain largely unclear. Using gene knock-out approaches, we and others have recently identified Bmi1 as an anti-aging...

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Detalles Bibliográficos
Autores principales: Yu, Jun, Wu, Yibo, Li, Hong, Zhou, Hui, Shen, Cong, Gao, Tingting, Lin, Meng, Dai, Xiuliang, Ou, Jian, Liu, Meiling, Huang, Xiaoyan, Zheng, Bo, Sun, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076678/
https://www.ncbi.nlm.nih.gov/pubmed/33928089
http://dx.doi.org/10.3389/fcell.2021.665089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076678/
https://www.ncbi.nlm.nih.gov/pubmed/33928089
http://dx.doi.org/10.3389/fcell.2021.665089

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