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BMI1 Drives Steroidogenesis Through Epigenetically Repressing the p38 MAPK Pathway

Testosterone biosynthesis progressively decreases in aging males primarily as a result of functional changes to Leydig cells. Despite this, the mechanisms underlying steroidogenesis remain largely unclear. Using gene knock-out approaches, we and others have recently identified Bmi1 as an anti-aging...

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Detalles Bibliográficos
Autores principales:	Yu, Jun, Wu, Yibo, Li, Hong, Zhou, Hui, Shen, Cong, Gao, Tingting, Lin, Meng, Dai, Xiuliang, Ou, Jian, Liu, Meiling, Huang, Xiaoyan, Zheng, Bo, Sun, Fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076678/ https://www.ncbi.nlm.nih.gov/pubmed/33928089 http://dx.doi.org/10.3389/fcell.2021.665089

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