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The Pharmacological or Genetic Blockade of Endogenous De Novo Fatty Acid Synthesis Does Not Increase the Uptake of Exogenous Lipids in Ovarian Cancer Cells

Ovarian cancer(OC) is a serious threat to women worldwide. Peritoneal dissemination, ascites and omental metastasis are typical features for disease progression, which occurs in a micro-environment that is rich in high-energy lipids. OC cells require high amounts of lipids for survival and growth. N...

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Detalles Bibliográficos
Autores principales: Grunt, Thomas W., Lemberger, Lisa, Colomer, Ramón, López−Rodríguez, María Luz, Wagner, Renate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076863/
https://www.ncbi.nlm.nih.gov/pubmed/33928023
http://dx.doi.org/10.3389/fonc.2021.610885