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Ecto-5′-Nucleotidase (CD73) Regulates the Survival of CD8+ T Cells

Ecto-5′-nucleotidase (CD73) is an enzyme present on the surface of tumor cells whose primary described function is the production of extracellular adenosine. Due to the immunosuppressive properties of adenosine, CD73 is being investigated as a target for new antitumor therapies. We and others have d...

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Detalles Bibliográficos
Autores principales: Rosemblatt, Mariana V., Parra-Tello, Brian, Briceño, Pedro, Rivas-Yáñez, Elizabeth, Tucer, Suat, Saavedra-Almarza, Juan, Hörmann, Pilar, Martínez, Brandon A., Lladser, Álvaro, Rosemblatt, Mario, Cekic, Caglar, Bono, María Rosa, Sauma, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076893/
https://www.ncbi.nlm.nih.gov/pubmed/33928082
http://dx.doi.org/10.3389/fcell.2021.647058