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Ecto-5′-Nucleotidase (CD73) Regulates the Survival of CD8+ T Cells
Ecto-5′-nucleotidase (CD73) is an enzyme present on the surface of tumor cells whose primary described function is the production of extracellular adenosine. Due to the immunosuppressive properties of adenosine, CD73 is being investigated as a target for new antitumor therapies. We and others have d...
Autores principales: | Rosemblatt, Mariana V., Parra-Tello, Brian, Briceño, Pedro, Rivas-Yáñez, Elizabeth, Tucer, Suat, Saavedra-Almarza, Juan, Hörmann, Pilar, Martínez, Brandon A., Lladser, Álvaro, Rosemblatt, Mario, Cekic, Caglar, Bono, María Rosa, Sauma, Daniela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076893/ https://www.ncbi.nlm.nih.gov/pubmed/33928082 http://dx.doi.org/10.3389/fcell.2021.647058 |
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