LCZ696 Attenuated Doxorubicin-Induced Chronic Cardiomyopathy Through the TLR2-MyD88 Complex Formation

BACKGROUND AND PURPOSE: The profibrotic and proinflammatory effects induced by doxorubicin (DOX) are key processes in the development of serious heart damage. Lack of effective drugs and the unclear mechanisms of its side effects limit the clinical treatment of DOX-induced cardiac injury. This study...

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Detalles Bibliográficos
Autores principales: Ye, Shiju, Su, Lan, Shan, Peiren, Ye, Bozhi, Wu, Shengjie, Liang, Guang, Huang, Weijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076895/
https://www.ncbi.nlm.nih.gov/pubmed/33928085
http://dx.doi.org/10.3389/fcell.2021.654051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8076895/
https://www.ncbi.nlm.nih.gov/pubmed/33928085
http://dx.doi.org/10.3389/fcell.2021.654051

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