Pharmacological inhibition of dynamin‐related protein 1 attenuates skeletal muscle insulin resistance in obesity

Dynamin‐related protein‐1 (Drp1) is a key regulator in mitochondrial fission. Excessive Drp1‐mediated mitochondrial fission in skeletal muscle under the obese condition is associated with impaired insulin action. However, it remains unknown whether pharmacological inhibition of Drp1, using the Drp1‐...

Descripción completa

Detalles Bibliográficos
Autores principales: Kugler, Benjamin A., Deng, Wenqian, Duguay, Abigail L., Garcia, Jessica P., Anderson, Meaghan C., Nguyen, Paul D., Houmard, Joseph A., Zou, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077121/
https://www.ncbi.nlm.nih.gov/pubmed/33904649
http://dx.doi.org/10.14814/phy2.14808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077121/
https://www.ncbi.nlm.nih.gov/pubmed/33904649
http://dx.doi.org/10.14814/phy2.14808

Ejemplares similares