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Pharmacological inhibition of dynamin‐related protein 1 attenuates skeletal muscle insulin resistance in obesity
Dynamin‐related protein‐1 (Drp1) is a key regulator in mitochondrial fission. Excessive Drp1‐mediated mitochondrial fission in skeletal muscle under the obese condition is associated with impaired insulin action. However, it remains unknown whether pharmacological inhibition of Drp1, using the Drp1‐...
Autores principales: | Kugler, Benjamin A., Deng, Wenqian, Duguay, Abigail L., Garcia, Jessica P., Anderson, Meaghan C., Nguyen, Paul D., Houmard, Joseph A., Zou, Kai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077121/ https://www.ncbi.nlm.nih.gov/pubmed/33904649 http://dx.doi.org/10.14814/phy2.14808 |
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