Loss‐of‐function or gain‐of‐function variations in VINCULIN (VCL) are risk factors of human neural tube defects

BACKGROUND: Neural tube defects (NTDs) are severe birth defects resulting from the failure of neural tube closure during embryogenesis. Both genetic and environmental factors contribute to the occurrence of NTDs and the heritability of NTDs is approximately 70%. As a key component of focal adhesions...

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Detalles Bibliográficos
Autores principales: Wang, Yalan, Qin, Yue, Peng, Rui, Wang, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077129/
https://www.ncbi.nlm.nih.gov/pubmed/33491343
http://dx.doi.org/10.1002/mgg3.1563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077129/
https://www.ncbi.nlm.nih.gov/pubmed/33491343
http://dx.doi.org/10.1002/mgg3.1563

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