Impact of regulatory light chain mutation K104E on the ATPase and motor properties of cardiac myosin

Mutations in the cardiac myosin regulatory light chain (RLC, MYL2 gene) are known to cause inherited cardiomyopathies with variable phenotypes. In this study, we investigated the impact of a mutation in the RLC (K104E) that is associated with hypertrophic cardiomyopathy (HCM). Previously in a mouse...

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Detalles Bibliográficos
Autores principales: Rasicci, David V., Kirkland, Orville, Moonschi, Faruk H., Wood, Neil B., Szczesna-Cordary, Danuta, Previs, Michael J., Wenk, Jonathan F., Campbell, Kenneth S., Yengo, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077168/
https://www.ncbi.nlm.nih.gov/pubmed/33891674
http://dx.doi.org/10.1085/jgp.202012811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077168/
https://www.ncbi.nlm.nih.gov/pubmed/33891674
http://dx.doi.org/10.1085/jgp.202012811

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