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Advanced oxidation protein products induce inflammatory responses and invasive behaviour in fibroblast-like synoviocytes via the RAGE-NF-κB pathway

AIMS: Rheumatoid arthritis (RA), which mainly results from fibroblast-like synoviocyte (FLS) dysfunction, is related to oxidative stress. Advanced oxidation protein products (AOPPs), which are proinflammatory mediators and a novel biomarker of oxidative stress, have been observed to accumulate signi...

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Detalles Bibliográficos
Autores principales: Lou, Aiju, Wang, Le, Lai, Weinan, Zhu, DingJi, Wu, Weirong, Wang, Zhao, Cai, Zihong, Yang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077182/
https://www.ncbi.nlm.nih.gov/pubmed/33827262
http://dx.doi.org/10.1302/2046-3758.104.BJR-2020-0085.R2