Rapid decay of host basal mRNAs during SARS-CoV-2 infection perturbs host antiviral mRNA biogenesis and export

A key feature of the mammalian innate immune response to viral infection is the transcriptional induction of interferon (IFN) genes, which encode for secreted proteins that prime the antiviral response and limit viral replication and dissemination. A hallmark of severe COVID-19 disease caused by SAR...

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Detalles Bibliográficos
Autores principales: Burke, James M., St Clair, Laura A., Perera, Rushika, Parker, Roy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077573/
https://www.ncbi.nlm.nih.gov/pubmed/33907748
http://dx.doi.org/10.1101/2021.04.19.440452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077573/
https://www.ncbi.nlm.nih.gov/pubmed/33907748
http://dx.doi.org/10.1101/2021.04.19.440452

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