Cargando…
Elucidation of SIRT-1/PGC-1α-associated mitochondrial dysfunction and autophagy in nonalcoholic fatty liver disease
BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) can lead to chronic liver diseases associated with mitochondrial damages. However, the exact mechanisms involved in the etiology of the disease are not clear. METHODS: To gain new insights, the changes affecting sirtuin 1 (SIRT-1) during liver fat...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077826/ https://www.ncbi.nlm.nih.gov/pubmed/33902605 http://dx.doi.org/10.1186/s12944-021-01461-5 |