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Elucidation of SIRT-1/PGC-1α-associated mitochondrial dysfunction and autophagy in nonalcoholic fatty liver disease

BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) can lead to chronic liver diseases associated with mitochondrial damages. However, the exact mechanisms involved in the etiology of the disease are not clear. METHODS: To gain new insights, the changes affecting sirtuin 1 (SIRT-1) during liver fat...

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Detalles Bibliográficos
Autores principales:	Jiang, Yan, Chen, Duankai, Gong, Qiming, Xu, Qunqing, Pan, Dong, Lu, Feiyan, Tang, Qianli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077826/ https://www.ncbi.nlm.nih.gov/pubmed/33902605 http://dx.doi.org/10.1186/s12944-021-01461-5

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