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Codon usage bias regulates gene expression and protein conformation in yeast expression system P. pastoris

BACKGROUND: Protein synthesis is one of the extremely important anabolic pathways in the yeast expression system Pichia pastoris. Codon optimization is a commonly adopted strategy for improved protein expression, although unexpected failures did appear sometimes waiting for further exploration. Rece...

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Detalles Bibliográficos
Autores principales: Xu, Yichun, Liu, Kunshan, Han, Yu, Xing, Yanzi, Zhang, Yuanxing, Yang, Qiuying, Zhou, Mian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077831/
https://www.ncbi.nlm.nih.gov/pubmed/33902585
http://dx.doi.org/10.1186/s12934-021-01580-9