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Minocycline attenuation of rat corpus callosum abnormality mediated by low-dose lipopolysaccharide-induced microglia activation

BACKGROUND: Microglia are resident innate immune cells in the brain, and activation of these myeloid cells results in secretion of a variety of pro-inflammatory molecules, leading to the development of neurodegenerative disorders. Lipopolysaccharide (LPS) is a widely used experimental stimulant in m...

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Detalles Bibliográficos
Autores principales: Zhang, Jingdong, Boska, Michael, Zheng, Ya, Liu, Jianuo, Fox, Howard S., Xiong, Huangui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077939/
https://www.ncbi.nlm.nih.gov/pubmed/33902641
http://dx.doi.org/10.1186/s12974-021-02142-x