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Minocycline attenuation of rat corpus callosum abnormality mediated by low-dose lipopolysaccharide-induced microglia activation
BACKGROUND: Microglia are resident innate immune cells in the brain, and activation of these myeloid cells results in secretion of a variety of pro-inflammatory molecules, leading to the development of neurodegenerative disorders. Lipopolysaccharide (LPS) is a widely used experimental stimulant in m...
Autores principales: | Zhang, Jingdong, Boska, Michael, Zheng, Ya, Liu, Jianuo, Fox, Howard S., Xiong, Huangui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077939/ https://www.ncbi.nlm.nih.gov/pubmed/33902641 http://dx.doi.org/10.1186/s12974-021-02142-x |
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